Afun VT 200 Vaginal Tablet

Indications

Afun VT rectal preparation effectively addresses vaginal itching, burning, and discharge associated with recurrent vaginal yeast infections (Vaginal candidiasis) and vaginitis due to Candida species, including Mycotic infections complicated by other microorganisms sensitive to the drug.

Pharmacology

Clotrimazole, a broad-spectrum antifungal agent, combats dermal infections caused by various pathogenic dermatophytes, yeasts, molds, and bacteroids. It also exhibits activity against certain gram-positive bacteria, especially Staphylococci, and Trichomonas. Clotrimazole alters fungal cell wall permeability by interfering with cell wall lipids, inhibiting ergosterol synthesis at fungistatic levels, and causing membrane damage at higher concentrations, unrelated to sterol synthesis.

Dosage

For initial infections, a 3-day treatment regimen with Clotrimazole 200 mg vaginal preparation is generally effective for Candida vaginitis. For re-infections or mixed infections, a 6-day treatment plan is recommended. Clotrimazole 100 mg vaginal preparation can be used nightly for six consecutive nights. Additionally, Clotrimazole 500 mg vaginal preparation offers a single-dose, complete treatment. Partners should undergo local treatment with Clotrimazole cream simultaneously to prevent re-infection.

Administration

To administer Clotrimazole vaginal preparation, pull out the plunger until it stops, place a vaginal tablet into the applicator, carefully insert the applicator containing the tablet as deeply as possible into the vagina while lying on your back, push the plunger until it stops to deposit the tablet, then remove the applicator. After use, clean the applicator thoroughly. Pregnant women should follow their physician’s instructions.

Interaction

Currently, there is no available information regarding interactions with other medications.

Contraindications

This product is contraindicated in patients with known hypersensitivity to any of its components.

Side Effects

Due to minimal absorption through vaginal skin, systemic effects of Afun VT are unlikely. Local tolerance is generally good, with rare instances of local irritation or burning, which are considered non-harmful.

Pregnancy & Lactation

Clotrimazole should be used during pregnancy only when deemed necessary by a physician. Studies indicate minimal absorption into the bloodstream and no adverse effects in women in their second or third trimesters. Its secretion in breast milk is unknown. Clotrimazole suppositories can be used during pregnancy under physician supervision.

Therapeutic Class

Afun VT falls under drugs used in Vaginal and Vulval conditions and belongs to the category of Topical Antifungal preparations.

Storage Conditions

Store below 25°C, away from light and moisture, and out of the reach of children.