Ceegram

Indications for Ceegram (Ascorbic Acid)

Ascorbic Acid (Ceegram) is commonly used to:

• Prevent and treat scurvy caused by vitamin C deficiency.
• Aid in the healing of wounds and fractures by supporting tissue repair.
• Contribute to the formation of collagen in connective tissues, promoting healthy skin and joints.
• Enhance iron absorption to prevent and treat anemia.
• Stimulate the production of hemoglobin and red blood cells in the bone marrow.
• Strengthen the immune system, helping to prevent infections, including colds.
• Promote healthy capillaries, gums, and teeth.

Always use Ceegram as directed by a registered healthcare professional.

Pharmacology

Ceegram (Ascorbic Acid) is a vital nutrient that the body cannot produce naturally, so it must be acquired through diet or supplements. This vitamin plays several key roles:

• Supports tissue growth and repair, adrenal function, and the immune system.
• Acts as a powerful antioxidant, protecting cells from damage due to pollution, infections, and oxidative stress.
• As a coenzyme, it is crucial for wound healing, drug metabolism, and the metabolism of cholesterol and folic acid.
• Promotes healthy hair, skin, and gums, contributing to overall well-being and vitality.

Dosage and Administration

Oral Tablets:

• For prevention of scurvy: 1 tablet daily.
• For treatment of scurvy: 1-2 tablets daily, with higher doses based on severity.
• For stroke risk reduction (elderly): 1-2 tablets daily.
• General use: 1 tablet daily or as advised by your doctor.
• Maximum safe dose: 2000 mg daily, divided into doses.

Oral Sachets:

• 1 sachet daily or as directed by a physician.
• Maximum dose: 2000 mg/day (up to 4 sachets).

Parenteral Administration:

• Intramuscular (IM) preferred for best absorption.
• For intravenous (IV) administration, dilute the solution in a large volume of saline, water, or glucose to avoid adverse reactions.
• Recommended dose for scurvy: 300 mg to 1g daily; higher doses may be used as needed.
• For wound healing: 300-500 mg daily for up to 10 days pre- and post-surgery.
• For severe burns: 1-2g daily, based on injury severity.
• Maximum dose: Can go up to 6g per day for certain conditions under medical supervision.

Always consult with a healthcare professional before using parenteral forms of Ceegram.

Drug Interactions

• Hazardous interactions: Ascorbic acid may interact with various drugs, including aminophylline, bleomycin, and chloramphenicol sodium succinate. It is not recommended to mix ascorbic acid with these medications.
• Beneficial interactions: Ascorbic acid enhances iron absorption and increases the half-life of paracetamol, improving its effectiveness.

Side Effects

Ceegram is generally safe, but high doses may lead to:

• Gastrointestinal issues like diarrhea and bloating.
• Iron over-absorption, potentially harmful in individuals with certain blood disorders.
• Hyperoxaluria and hyperuricosuria, particularly in patients with a history of kidney stones.

Excessive use during pregnancy (more than 5g/day) may lead to complications, including fetal abortion.

Pregnancy and Lactation

Ceegram is safe in standard doses during pregnancy and lactation. However, high doses (above 5g/day) should be avoided during pregnancy due to potential risks to the fetus.

Precautions and Warnings

• Megadoses of vitamin C (over 1000 mg daily) should be avoided, especially during pregnancy, as they may cause adverse effects such as scurvy in newborns.
• False positive results may occur in certain lab tests (glucose, creatine, uric acid) due to the reactive nature of Ceegram.

Storage Instructions

Store Ceegram in a cool, dry place at temperatures below 30°C, away from direct light and moisture.