Odycin Eye Drop

Indications

Odycin ophthalmic solution is designed for the effective treatment of bacterial conjunctivitis caused by specific bacterial strains. It targets:

• Aerobic Gram-positive bacteria: Corynebacterium species, Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus warneri, Streptococcus pneumoniae, Streptococcus viridans group.
• Aerobic Gram-negative bacteria: Acinetobacter lwoffii, Haemophilus influenzae, Haemophilus parainfluenzae.
• Other bacteria: Chlamydia trachomatis.

Additionally, Odycin is used as an intraocular injection to prevent postoperative bacterial endophthalmitis.

Pharmacology

Odycin contains Moxifloxacin, a potent antimicrobial agent that works by inhibiting bacterial topoisomerase II (DNA gyrase) and topoisomerase IV. These enzymes are crucial for bacterial DNA replication, transcription, and repair, as well as chromosomal DNA partitioning during cell division.

Dosage & Administration

• Eye Drops: Administer one drop into the affected eye three times daily for 7 days.
• Eye Ointment: Apply a thin layer to the affected eye three times daily for the first two days, then reduce to twice daily for the following five days, or as directed by your physician.
• Intraocular Injection: Administer 0.2-0.4 ml of Moxifloxacin prior to ocular surgery. The exact dose will be determined by your doctor.

Interactions

Odycin ophthalmic solution is unlikely to interact with other medications, as it does not inhibit key cytochrome P450 enzymes.

Contraindications

Do not use Odycin if you have a known hypersensitivity to Moxifloxacin, other quinolones, or any component of the formulation.

Side Effects

Common ocular side effects include conjunctivitis, reduced visual acuity, dry eye, keratitis, discomfort, hyperemia, pain, itching, subconjunctival hemorrhage, and tearing. Non-ocular side effects reported include fever, cough, infections, otitis media, pharyngitis, rash, and rhinitis.

Pregnancy & Lactation

Odycin should be used during pregnancy only if the benefits outweigh potential risks to the fetus. It is unknown if Moxifloxacin is excreted in human milk, so caution is advised when administering to nursing mothers.

Precautions & Warnings

Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi. Discontinue use if superinfection occurs and initiate alternative treatment. Patients should avoid wearing contact lenses if they exhibit symptoms of bacterial conjunctivitis. Use magnification, such as slit lamp biomicroscopy, for examination as needed.

Therapeutic Class

Ophthalmic Antibacterial Agents

Storage Conditions

Store below 25°C, away from light, and protect from freezing. Keep out of reach of children and avoid contaminating the dropper tip. Discard one month after opening.