Bizoran 10/40
330.00৳ Strip
- Bizoran is a potent combination medication for hypertension management.
- Contains Amlodipine, a calcium channel blocker, and Olmesartan Medoxomil, an angiotensin II receptor blocker.
- Reduces peripheral vascular resistance and counters vasoconstriction effectively.
- Administered once daily with dosage adjustments as per patient response.
- Ensure optimal storage conditions for maintaining efficacy.
Brand
|
Beximco Pharmaceuticals Ltd |
|---|---|
Generics
|
Amlodipine Besilate + Olmesartan Medoxomil |
Type
|
Tablet |
Indications
Bizoran is indicated for the treatment of hypertension either alone or in combination with other antihypertensive agents. It is particularly suitable as initial therapy in patients requiring multiple medications to achieve their blood pressure goals. Treatment decisions should consider individual factors such as baseline blood pressure and target goals.
Pharmacology
Bizoran combines Amlodipine, a dihydropyridine calcium channel blocker that reduces peripheral vascular resistance, with Olmesartan Medoxomil, an angiotensin II receptor blocker that inhibits the vasoconstrictor and aldosterone-secreting effects of angiotensin II.
Dosage & Administration
Start with Bizoran 5/20 mg once daily, titrating up to a maximum of 10/40 mg once daily as needed. Adjustments may be necessary for elderly patients and those with hepatic impairment.
Interaction
Monitor blood pressure, renal function, and electrolytes closely when combining Bizoran with NSAIDs or selective COX-2 inhibitors.
Contraindications
Bizoran is contraindicated in patients with diabetes using Aliskiren, particularly during pregnancy’s second and third trimesters due to potential fetal harm.
Side Effects
Common side effects include peripheral edema, headache, flushing, dizziness, and rare instances of sprue-like enteropathy.
Pregnancy & Lactation
Pregnancy Category D: Avoid use during pregnancy’s later stages. Discontinue breastfeeding or the drug, taking into account its importance to the mother.
Precautions & Warnings
Use Bizoran cautiously in patients with volume depletion, severe aortic stenosis, or severe obstructive coronary artery disease to mitigate risks of hypotension, vasodilation, or exacerbated angina.
Use in Special Populations
Safety and effectiveness in pediatric patients, those with renal impairment, or hepatic impairment have not been established.
Overdose Effects
No specific information on human overdoses is available.
Therapeutic Class
Combined antihypertensive preparations
Storage Conditions
Store Bizoran below 30°C, away from light, and out of reach of children.
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