Sulprex 3ml Solution

Indications

Salbutamol sulfate & Ipratropium bromide solution for inhalation is used to treat reversible bronchospasm in patients with obstructive airway diseases who require more than one bronchodilator.

Description

This inhalation solution combines Salbutamol Sulphate and Ipratropium Bromide, potent bronchodilators. Salbutamol acts on airway smooth muscles, while Ipratropium inhibits vagally mediated reflexes. Together, they provide superior bronchodilation without systemic side effects, targeting the lungs locally.

Pharmacology

Ipratropium Bromide is minimally absorbed systemically after inhalation. Salbutamol is rapidly absorbed, reaching peak plasma concentrations within hours and is primarily excreted unchanged in urine.

Dosage

Administer one 3 ml ampoule via nebulizer four times daily in adults (including elderly). Children’s usage should be determined by a doctor.

Administration

1. Twist off the ampoule top and hold it upright.
2. Squeeze the required nebulizer solution amount into the chamber.
3. Follow physician’s directions for dilution if needed.

Interaction

Avoid concurrent use with other beta-mimetics, systemically absorbed anticholinergics, or xanthine derivatives to minimize side effects.

Contraindications

Not recommended for patients with hypertrophic obstructive tachyarrhythmia or hypersensitivity to atropine derivatives.

Side Effects

Common side effects include skeletal muscle tremors and nervousness. Serious adverse effects may include hypokalaemia and respiratory issues.

Pregnancy & Lactation

Category C in pregnancy; caution advised during breastfeeding due to potential excretion in milk.

Precautions & Warnings

Consult a doctor immediately in case of acute dyspnoea. Hypersensitivity reactions may occur post-administration.

Overdose Effects

Monitor for symptoms like tachycardia and arrhythmias. Administer appropriate supportive therapy if needed.

Therapeutic Class

Combined bronchodilators

Storage Conditions

Store below 30°C, protect from light and moisture, and keep out of children’s reach.