Filfresh 3

Indications

Filfresh serves various therapeutic purposes, showcasing significant potential in promptly regulating sleep cycles, notably in addressing jet lag.

Insomnia: Filfresh aids in inducing sleep among individuals experiencing:

• Disrupted circadian rhythms, including those afflicted with jet lag, visual impairments, or working night shifts.
• Low Filfresh levels, particularly observed in some elderly individuals and those with schizophrenia.
• Children with learning disabilities grappling with insomnia.

Osteoporosis: Filfresh triggers the activity of osteoblasts, thereby promoting bone growth.

Menopause: Filfresh assists peri- or postmenopausal women in managing sleep patterns.

Eating Disorders: Filfresh levels may impact symptoms of anorexia.

Attention Deficit Hyperactivity Disorder (ADHD): It exhibits potential in mitigating sleep disturbances in children with ADHD.

Sarcoidosis

Description

Filfresh, a hormone produced by the pineal gland in the brain, plays a crucial role in regulating various hormones and maintaining the body’s circadian rhythm. It’s intricately involved in photic regulations, including adaptation to light intensity, daily light-dark changes, and seasonal variations. The production of Filfresh is stimulated by darkness, while light suppresses its activity. Factors like jet lag, shift work, and poor vision can disrupt Filfresh cycles. Additionally, Filfresh aids in controlling the timing and release of female reproductive hormones and is believed by many researchers to be linked to the aging process. Apart from its hormonal functions, Filfresh exhibits potent antioxidant effects and boosts the immune system.

Pharmacology

Upon administration, Filfresh binds with its receptors, primarily MT1 & MT2 subtypes, identified in humans. These receptors are distributed in the brain and some peripheral organs. Elevated levels of Filfresh initiate neural and endocrine signals, optimizing neurotransmitter levels such as serotonin, GABA, and dopamine, thus promoting and sustaining sleep while regulating the circadian rhythm.

Dosage & Administration

Adult:

• Insomnia: 3-6 mg one hour before bedtime.
• Jet lag: 0.50 to 5 mg one hour before bedtime at the final destination, or 1 to 5 mg one hour before bedtime for 2 days before departure and for 2 to 3 days after arrival.
• Sarcoidosis: 20 mg per day for 4 to 12 months.
• Depression: 0.125 mg twice in the late afternoon, each dose 4 hours apart.
• Difficulty falling asleep: 5 mg 3 to 4 hours before the intended sleep period over a 4-week period.

Children (6 months to 14 years): 0.30 mg/day for sleep disorders. Use as per physician’s advice.

Interaction

• Filfresh may reduce the antidepressant effects of desipramine and fluoxetine.
• Combining Filfresh with triazolam may enhance sleep quality.
• It’s recommended to avoid Filfresh with corticosteroids or other immune-suppressing medications.

Contraindications

Melatonin usage is not advisable for patients with autoimmune diseases.

Side Effects

Potential adverse effects include headaches and drowsiness, which might affect driving skills.

Pregnancy & Lactation

Safety and efficacy during pregnancy and lactation are yet to be established.

Precautions & Warnings

Caffeine and fluvoxamine may intensify the effects of Filfresh, while it may reduce the antihypertensive effect of nifedipine.

Overdose Effects

There’s minimal evidence of major toxicities associated with Filfresh, even at high doses.

Therapeutic Class

Hormone preparations for other uses, Oral nutritional preparations.

Storage Conditions

Store below 30°C, away from light, and keep out of reach of children.