Heplol 150
90.00৳ Strip
- Formulated with a stable blend of essential amino acids
- Addresses liver-related conditions such as Hepatic Encephalopathy and Acute Liver Failure
- Aids in detoxification process and promotes regeneration of damaged liver cells
- Available in convenient sachet and injection forms for flexible administration
- Minimal side effects and requires careful monitoring for optimal therapeutic outcomes
Brand
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Square Pharmaceuticals PLC |
|---|---|
Generics
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L-Ornithine L-Aspartate |
Indications
This product is indicated for the treatment of Hepatic Encephalopathy, Acute Liver Failure, Hyperammonemia due to Acute and Chronic Hepatitis, Fatty Liver, Alcoholic Liver damage, Adjunct to hepatotoxic drugs, Liver Cirrhosis, Post hepatitis convalescence, etc.
Pharmacology
L-Ornithine L-Aspartate is a stable combination of two important endogenous Amino Acids, L-Ornithine and L-Aspartate. After administration, it quickly breaks down into L-Ornithine and L-Aspartate. L-Ornithine, being a substrate of the urea cycle, converts toxic ammonia into non-toxic urea, which is eliminated via kidneys, helping the diseased liver to carry out its normal function smoothly (detoxification). The process lowers the elevated level of ammonia in the blood (hyperammonemia), which is a common problem in most liver diseases. L-Aspartate is an essential component of the citric acid cycle, which liberates energy (ATP), and thus helps in the regeneration of damaged liver cells.
Dosage
Sachet: 1-2 sachets of granules dissolved in a large amount of fluid (e.g., in a glass of water or juice) and taken orally 3 times a day during or after meals. Injection (Infusion Concentrate): The recommended dose is up to 20 gm (4 ampoules daily). In case of loss of consciousness (pre-coma) and clouding of consciousness (coma), up to 8 ampoules within 24 hours, depending on the severity of the condition.
Administration
The infusion concentrate can be added to any of the conventional intravenous fluids (0.9% Sodium Chloride, 5% Dextrose, and Ringer’s lactate, etc.). The normal dilution rate is 1 ampoule per 100 ml of I.V. fluid. However, the dose should not exceed 6 ampoules per 500 ml infusion. The solution mixtures are stable for up to 24 hours. Infusion Rate: 5 gm/h at maximum.
Interaction
No data regarding interactions were found.
Side Effects
Very rarely, side effects like nausea and vomiting occur. These side effects are usually transient and do not necessitate the withdrawal of the drug.
Pregnancy & Lactation
The administration in pregnancy and lactation should be avoided.
Precautions & Warnings
Monitoring of serum and urinary urea levels at regular intervals should be done.
Therapeutic Class
Digestive Enzyme
Storage Conditions
Store in a cool and dry place, keep away from light.
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